Tips to open MOL2 file
Can't open the MOL2 file? You are not the only one. Thousands of users face similar problems every day. Below you will find tips on how to open MOL2 files as well as a list of programs that support MOL2 files.
MOL2 file extension
| File Name |
Portable Representation Of A SYBYL Molecule |
| File Developer |
Tripos, L.P. |
| File Category |
Misc Files |
The MOL2 file is supported on 1 operating systems. Depending on your operating system, you may need different software to handle the MOL2 files. Below is a summary of the number of programs that support and open the MOL2 file on each system platform.
What is MOL2 file?
The file in the MOL2 format belongs to the Misc Files category. It was designed by Tripos, L.P.. Additionally, the Misc Files category contains 6033 of other files. Portable Representation Of A SYBYL Molecule is supported by 1 operating systems. Although it can be found with greater or lesser success on any operating system, it will only be useful on Windows. The main program that supports this format is Sybyl. This was created by Tripos, L.P..
How to open MOL2 file?
An often recurring problem with Portable Representation Of A SYBYL Molecule is that MOL2 is not associated with the correct program file. Thus, when you open MOL2, the program selection wizard or some other program starts. This can be quickly resolved by following the instructions below.
The first thing you should do is just "doubleclick" on the MOL2 file icon you want to open. If the operating system has an appropriate application to support it and there is also an association between the file and the program, the file should be opened.
Step 1. Install Sybyl
An often overlooked issue is to make sure that Sybyl is installed on the computer. The easiest method is to use the system search engine by entering the program name Sybyl in it. If it is not, installation may solve the problem, as most applications create file associations during installation. Below is a list of programs that support the file MOL2.
Programs to open MOL2 file
Remember to download programs supporting MOL2 files only from verified and safe sources. We suggest using the websites of software developers.
Step 2. Create association of Sybyl with MOL2 files
However, it may happen that the application itself does not cause the MOL2 file to open in the Sybyl application, but you can set it manually. It is most convenient to call the context menu with the right mouse button and select Properties. Information about the file and the program that the file is associated with are available here. Changes can be made using the "Change" button. If there is no software on the list, simply select "Browse" and manually select the directory where the application is installed. Checking the "Always use the selected program ..." box will permanently associate the MOL2 file with the Sybyl program.
Step 3. Update Sybyl to the latest version
The fault may also lie with the Sybyl program, it is possible that Portable Representation Of A SYBYL Molecule requires a newer version of the program. Some applications allow you to update from the program level, and for others you need to download the installer from the Tripos, L.P. page and install.
Step 4. Check for the following problems with the MOL2 file
If the above steps do not help, you can assume that the file itself is not correct. The most common file problems are:
The affected file may be 0 KB or smaller than expected. Usually this applies to MOL2 files downloaded from the Internet in case the download did not finish properly. The only repair option is to download the file again.
The most common cause here is computer viruses. A quick virus scan using an up-to-date antivirus program should clear up any doubts. Some antivirus vendors also provide free online scanners. The scan should cover the entire computer, not only the MOL2 file that we want to open. As a result of the scan, sometimes it is not possible to recover MOL2 files, which are deleted if there is a backup of this file, then after restoring it, it must also be scanned.
Older version of MOL2 file may not always be supported by the latest software version. These problems are known and are often very easy to fix using the software developers's website.
There can be many reasons for this. Repairing is very dependent on the file type. Some programs offer the ability to automatically repair MOL2 file corruption. You can restore the file from a backup or use Tripos, L.P. help.
The program can also signal the fact of encryption. The encrypted MOL2 files cannot be played on other computers than the one on which they were encrypted, they must be decrypted before using on another device.
Some operating systems do not allow file operations in certain locations, eg in system directories or directly on the system drive. While there is usually no problem reading such a file, it may not be possible to save it. If possible, you can try to move the MOL2 file to another location.
This problem only occurs with more complex files. In this case, the MOL2 file is blocked by the first application to open it. Closing other programs should help. Sometimes it is necessary to wait a while before referencing the MOL2 file again. Some anti-virus or backup software may occupy the MOL2 file for a certain period of time. If the problem persists, restart the machine.
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