Tips to open CML file

Can't open the CML file? You are not the only one. Thousands of users face similar problems every day. Below you will find tips on how to open CML files as well as a list of programs that support CML files.

CML file extension

File Name Chemical Markup Language Format
File Category Data Files

The CML file is supported on 3 operating systems. Depending on your operating system, you may need different software to handle the CML files. Below is a summary of the number of programs that support and open the CML file on each system platform.

Operating systems
  • 2
  • 3
  • 1
  • 0
  • 0
  • 0

What is CML file?

The CML file has been categorized as Data Files. Additionally, the Data Files category contains 1326 of other files. Chemical Markup Language Format appears on 3 operating systems as a functional file. These systems consist of Linux, Mac OS, Windows, although it may occasionally be found on another system, it will be non-functional. Alternatively, you can use 5 other programs. You can use Bioclipse, iBabel in case Avogadro cannot be used.

How to open CML file?

The main problem with Chemical Markup Language Format is that the CML file is incorrectly associated with programs. Thus, when you open CML, the program selection wizard or some other program starts. This can be quickly resolved by following the instructions below.

The first thing you should do is just "doubleclick" on the CML file icon you want to open. If the operating system has an appropriate application to support it and there is also an association between the file and the program, the file should be opened.

Step 1. Install Avogadro

In this case, you should first verify that the Avogadro application is installed on the computer. The easiest method is to use the system search engine by entering the program name Avogadro in it. If it is not, installation may solve the problem, as most applications create file associations during installation. Below you will find a list of applications that support CML files.

Programs to open CML file

Remember to download programs supporting CML files only from verified and safe sources. We suggest using the websites of software developers.

Step 2. Create association of Avogadro with CML files

If the application is or has been freshly installed, but the CML file still does not use the Avogadro program, it means no association. The association can be created using the drop-down list available by right-clicking on the file and selecting Properties. The displayed window will contain information about the program that supports this type of file. Changes can be made using the "Change" button. It may happen that in the next window there will be no appropriate program - however, this can be corrected with the "Browse" option where you should manually indicate the program location. Checking the "Always use the selected program ..." box will permanently associate the CML file with the Avogadro program.

Step 3. Update Avogadro to the latest version

The fault may also lie with the Avogadro program, it is possible that Chemical Markup Language Format requires a newer version of the program.

Step 4. Check for the following problems with the CML file

Of course, it may happen that despite the above steps, the file still does not work. File problems can be divided into the following:

The CML file may be unusually small compared to the original file. Usually this applies to CML files downloaded from the Internet in case the download did not finish properly. The file should be downloaded again, making sure that the process has finished correctly.
The computer may have fallen victim to a computer virus or hacker. A quick virus scan using an up-to-date antivirus program should clear up any doubts. Some antivirus vendors also provide free online scanners. For the best results, we will scan the entire operating system, not just our CML file. As a result of the scan, sometimes it is not possible to recover CML files, which are deleted if there is a backup of this file, then after restoring it, it must also be scanned.
Older version of CML file may not always be supported by the latest software version. Help should be sought from the software developer, as they usually recommend using free file converters or installing an older version of the program.
There can be many reasons for this. Depending on the type of file, it is necessary to repair it accordingly. Some programs offer the ability to automatically repair CML file corruption.
The program indicates that the file is encrypted or corrupted. The encrypted file CML except for the special designation, works normally, but only on the device where it was encrypted, before transferring it to another machine, decryption is required.
Some of the system directories are excluded from modification. While there is usually no problem reading such a file, it may not be possible to save it. Copying the CML file to another location will fix the problem.
This can happen on a file that does not support multiple access. You may find that another program you are using is preventing you from working with the file. Closing other programs should help. Sometimes it is necessary to wait a while before referencing the CML file again. Antivirus programs or a backup being made may lock the file for a while without the user's knowledge. If the problem persists, restart the machine.